Towards Targeting PI3K-Dependent Regulation of Gene Expression in Brain Cancer

The PI3K pathway is one of the most highly perturbed cell signaling pathways in human cancer, including the most common malignant brain tumors, gliomas, where either activating mutations of positive pathway effectors or loss/inactivation of pathway inhibitors occurs. Knowledge of the precise transcr...

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Bibliographic Details
Main Author: Theo Mantamadiotis
Format: Article
Language:English
Published: MDPI AG 2017-05-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/9/6/60