A high-throughput method to examine protein-nucleotide interactions identifies targets of the bacterial transcriptional regulatory protein fur.

The Ferric uptake regulatory protein (Fur) is a transcriptional regulatory protein that functions to control gene transcription in response to iron in a number of pathogenic bacteria. In this study, we applied a label-free, quantitative and high-throughput analysis method, Interferometric Reflectanc...

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Bibliographic Details
Main Authors: Chunxiao Yu, Carlos A Lopez, Han Hu, Yu Xia, David S Freedman, Alexander P Reddington, George G Daaboul, M Selim Unlü, Caroline Attardo Genco
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4014563?pdf=render