Dietary sphingomyelin lowers hepatic lipid levels and inhibits intestinal cholesterol absorption in high-fat-fed mice.

Dietary sphingomyelin lowers hepatic lipid levels and inhibits intestinal cholesterol absorption in high-fat-fed mice.

Controlling intestinal lipid absorption is an important strategy for maintaining lipid homeostasis. Accumulation of lipids in the liver is a major risk factor for metabolic syndrome and nonalcoholic fatty liver disease. It is well-known that sphingomyelin (SM) can inhibit intestinal cholesterol abso...

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Bibliographic Details
Main Authors: Rosanna W S Chung, Alvin Kamili, Sally Tandy, Jacquelyn M Weir, Raj Gaire, Gerard Wong, Peter J Meikle, Jeffrey S Cohn, Kerry-Anne Rye
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23409094/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23409094/?tool=EBI

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