Renal and vascular effects of kallikrein inhibition in a model of Lonomia obliqua venom-induced acute kidney injury.

Renal and vascular effects of kallikrein inhibition in a model of Lonomia obliqua venom-induced acute kidney injury.

BACKGROUND:Lonomia obliqua venom is nephrotoxic and acute kidney injury (AKI) is the main cause of death among envenomed victims. Mechanism underlying L. obliqua-induced AKI involves renal hypoperfusion, inflammation, tubular necrosis and loss of glomerular filtration and tubular reabsorption capaci...

Full description

Bibliographic Details
Main Authors: Markus Berger, João Alfredo de Moraes, Walter Orlando Beys-da-Silva, Lucélia Santi, Paula Barros Terraciano, David Driemeier, Elizabeth Obino Cirne-Lima, Eduardo Pandolfi Passos, Maria Aparecida Ribeiro Vieira, Thereza Christina Barja-Fidalgo, Jorge Almeida Guimarães
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-02-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC6392336?pdf=render

Internet

http://europepmc.org/articles/PMC6392336?pdf=render

Similar Items