Cancer-Associated Fibroblasts: Versatile Players in the Tumor Microenvironment

Cancer-Associated Fibroblasts: Versatile Players in the Tumor Microenvironment

Cancer-associated fibroblasts (CAFs) are indispensable architects of the tumor microenvironment. They perform the essential functions of extracellular matrix deposition, stromal remodeling, tumor vasculature modulation, modification of tumor metabolism, and participation in crosstalk between cancer...

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Bibliographic Details
Main Authors: Debolina Ganguly, Raghav Chandra, John Karalis, Martha Teke, Todd Aguilera, Ravikanth Maddipati, Megan B. Wachsmann, Dario Ghersi, Giulia Siravegna, Herbert J. Zeh III, Rolf Brekken, David T. Ting, Matteo Ligorio
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
cancer-associated fibroblasts
tumor microenvironment
heterogeneity
hallmarks of cancer
chemoresistance
immunomodulation
Online Access:https://www.mdpi.com/2072-6694/12/9/2652

Internet

https://www.mdpi.com/2072-6694/12/9/2652

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