Autophagy and Tau Protein

Autophagy and Tau Protein

Neurofibrillary tangles, which consist of highly phosphorylated tau protein, and senile plaques (SPs) are pathological hallmarks of Alzheimer’s disease (AD). In swollen axons, many autophagic vacuoles are observed around SP in the AD brain. This suggests that autophagy function is disturbed in AD. W...

Full description

Bibliographic Details
Main Authors: Tadanori Hamano, Soichi Enomoto, Norimichi Shirafuji, Masamichi Ikawa, Osamu Yamamura, Shu-Hui Yen, Yasunari Nakamoto
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
autophagy
Alzheimer’s disease
tau protein
amyloid β protein
autophagic vacuoles
mTORC1
Online Access:https://www.mdpi.com/1422-0067/22/14/7475

Internet

https://www.mdpi.com/1422-0067/22/14/7475

Similar Items