Genetic variation in telomere maintenance genes, telomere length and breast cancer risk.

Telomeres at the ends of eukaryotic chromosomes play a critical role in maintaining the integrity and stability of the genome and participate in the initiation of DNA damage/repair responses.We performed a case-control study to evaluate the role of three SNPs (TERT-07, TERT-54 and POT1-03) in telome...

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Bibliographic Details
Main Authors: Jing Shen, Mary Beth Terry, Yuyan Liao, Irina Gurvich, Qiao Wang, Ruby T Senie, Regina M Santella
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3435409?pdf=render