Side population in human non-muscle invasive bladder cancer enriches for cancer stem cells that are maintained by MAPK signalling.

Side population in human non-muscle invasive bladder cancer enriches for cancer stem cells that are maintained by MAPK signalling.

Side population (SP) and ABC transporter expression enrich for stem cells in numerous tissues. We explored if this phenotype characterised human bladder cancer stem cells (CSCs) and attempted to identify regulatory mechanisms. Focusing on non-muscle invasive bladder cancer (NMIBC), multiple human ce...

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Bibliographic Details
Main Authors: Anastasia C Hepburn, Rajan Veeratterapillay, Stuart C Williamson, Amira El-Sherif, Neha Sahay, Huw D Thomas, Alejandra Mantilla, Robert S Pickard, Craig N Robson, Rakesh Heer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3511341?pdf=render

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http://europepmc.org/articles/PMC3511341?pdf=render

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