Synthesis and Selective Cytotoxic Activities on Rhabdomyosarcoma and Noncancerous Cells of Some Heterocyclic Chalcones

Chemically diverse heterocyclic chalcones were prepared and evaluated for cytotoxicity, aiming to push forward potency and selectivity. They were tested against rhabdomyosarcoma (RMS) and noncancerous cell line (LLC-PK1). The influence of heteroaryl patterns on rings A and B was studied. Heterocycle...

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Bibliographic Details
Main Authors: Tuong-Ha Do, Dai-Minh Nguyen, Van-Dat Truong, Thi-Hong-Tuoi Do, Minh-Tri Le, Thanh-Quan Pham, Khac-Minh Thai, Thanh-Dao Tran
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:Molecules
Subjects:
MTT
Online Access:http://www.mdpi.com/1420-3049/21/3/329