The Gq signalling pathway inhibits brown and beige adipose tissue
Brown and beige adipose tissues contribute to organismal energy expenditure by generating heat. Here, Klepac et al. survey G protein-coupled receptors in brown fat and show that Gq-coupled receptors inhibit expression of thermogenic proteins in mice and in human adipocytes.
Main Authors: | , , , , , , , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2016-03-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms10895 |