Effects of escitalopram and paroxetine on mTORC1 signaling in the rat hippocampus under chronic restraint stress

Effects of escitalopram and paroxetine on mTORC1 signaling in the rat hippocampus under chronic restraint stress

Abstract Background Recent studies have suggested that the activation of mammalian target of rapamycin (mTOR) signaling may be related to antidepressant action. Therefore, the present study evaluated whether antidepressant drugs would exert differential effects on mTOR signaling in the rat hippocamp...

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Bibliographic Details
Main Authors: Mi Kyoung Seo, Cheol Min Choi, Roger S. McIntyre, Hye Yeon Cho, Chan Hong Lee, Rodrigo B. Mansur, Yena Lee, Jae-Hon Lee, Young Hoon Kim, Sung Woo Park, Jung Goo Lee
Format: Article
Language:English
Published: BMC 2017-04-01
Series:BMC Neuroscience
Subjects:
Chronic restraint stress
Hippocampus
mTOR signaling
Antidepressants
Neuroplasticity
Online Access:http://link.springer.com/article/10.1186/s12868-017-0357-0

Internet

http://link.springer.com/article/10.1186/s12868-017-0357-0

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