Alanine Aminotransferase as a Monitoring Biomarker in Children with Nonalcoholic Fatty Liver Disease: A Secondary Analysis Using TONIC Trial Data

Alanine Aminotransferase as a Monitoring Biomarker in Children with Nonalcoholic Fatty Liver Disease: A Secondary Analysis Using TONIC Trial Data

Background: Validated noninvasive biomarkers to assess treatment response in pediatric nonalcoholic fatty liver disease (NAFLD) are lacking. We aimed to validate alanine aminotransferase (ALT), a monitoring biomarker for change in liver histology. Methods: A retrospective analysis using data from th...

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Bibliographic Details
Main Authors: Idil Arsik, Jennifer K. Frediani, Damon Frezza, Wen Chen, Turgay Ayer, Pinar Keskinocak, Ran Jin, Juna V. Konomi, Sarah E. Barlow, Stavra A. Xanthakos, Joel E. Lavine, Miriam B. Vos
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Children
Subjects:
NASH
ALT
pediatrics
fibrosis
Online Access:http://www.mdpi.com/2227-9067/5/6/64

Internet

http://www.mdpi.com/2227-9067/5/6/64

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