Genomic, microbial and environmental standardization in animal experimentation limiting immunological discovery

Abstract Background The use of inbred mice housed under standardized environmental conditions has been critical in identifying immuno-pathological mechanisms in different infectious and inflammatory diseases as well as revealing new therapeutic targets for clinical trials. Unfortunately, only a smal...

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Bibliographic Details
Main Authors: Josue Enriquez, Brianyell Mc Daniel Mims, Scott Trasti, Kathryn L. Furr, Matthew B. Grisham
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Immunology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12865-020-00380-x