Depletion in LpA-I:A-II particles enhances HDL-mediated endothelial protection in familial LCAT deficiency[S]

The aim of this study was to evaluate the vasoprotective effects of HDL isolated from carriers of LCAT deficiency, which are characterized by a selective depletion of LpA-I:A-II particles and predominance of preβ migrating HDL. HDLs were isolated from LCAT-deficient carriers and tested in vitro for...

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Main Authors: Monica Gomaraschi, Alice Ossoli, Samuela Castelnuovo, Sara Simonelli, Chiara Pavanello, Gloria Balzarotti, Marcello Arca, Alessia Di Costanzo, Tiziana Sampietro, Gaetano Vaudo, Damiano Baldassarre, Fabrizio Veglia, Guido Franceschini, Laura Calabresi
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Journal of Lipid Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520338359