Structural basis of HCV neutralization by human monoclonal antibodies resistant to viral neutralization escape.

Structural basis of HCV neutralization by human monoclonal antibodies resistant to viral neutralization escape.

The high mutation rate of hepatitis C virus allows it to rapidly evade the humoral immune response. However, certain epitopes in the envelope glycoproteins cannot vary without compromising virus viability. Antibodies targeting these epitopes are resistant to viral escape from neutralization and unde...

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Bibliographic Details
Main Authors: Thomas Krey, Annalisa Meola, Zhen-Yong Keck, Laurence Damier-Piolle, Steven K H Foung, Felix A Rey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23696737/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23696737/pdf/?tool=EBI

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