Further improvements of the P. falciparum humanized mouse model.

BACKGROUND: It has been shown previously that it is possible to obtain growth of Plasmodium falciparum in human erythrocytes grafted in mice lacking adaptive immune responses by controlling, to a certain extent, innate defences with liposomes containing clodronate (clo-lip). However, the reproducibi...

Full description

Bibliographic Details
Main Authors: Ludovic Arnold, Rajeev Kumar Tyagi, Pedro Meija, Claire Swetman, James Gleeson, Jean-Louis Pérignon, Pierre Druilhe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3069031?pdf=render