An efficient system for intestinal on-site butyrate production using novel microbiome-derived esterases

Abstract Short-chain fatty acids, especially butyrate, play beneficial roles in sustaining gastrointestinal health. However, due to limitations associated with direct consumption of butyrate, there has been interest in using prodrugs of butyrate. Tributyrin (TB), a triglyceride composed of three but...

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Bibliographic Details
Main Authors: Dah Hyun Jung, Ji Hyun Yong, Wontae Hwang, Mi Young Yoon, Sang Sun Yoon
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Journal of Biological Engineering
Subjects:
Online Access:https://doi.org/10.1186/s13036-021-00259-4