Thrombin Generation and Platelet Function in ICU Patients Undergoing CVVHD Using Regional Citrate Anticoagulation

Background: To investigate pro- and anticoagulant alterations in uremic critically ill patients prior to and during continuous renal replacement therapy. In addition to the conventional thrombin generation assay (TGA), we performed a thrombomodulin-modified variant to better elucidate procoagulant i...

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Bibliographic Details
Main Authors: Marion Wiegele, Lukas Infanger, Conrad Lacom, Stefan Koch, Andreas Baierl, Eva Schaden
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.680540/full