Epigenetic Activation of Pro-angiogenic Signaling Pathways in Human Endothelial Progenitors Increases Vasculogenesis

Epigenetic Activation of Pro-angiogenic Signaling Pathways in Human Endothelial Progenitors Increases Vasculogenesis

Summary: Human endothelial colony-forming cells (ECFCs) represent a promising source of adult stem cells for vascular repair, yet their regenerative capacity is limited. Here, we set out to understand the molecular mechanism restricting the repair function of ECFCs. We found that key pro-angiogenic...

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Bibliographic Details
Main Authors: Sylvain Fraineau, Carmen G. Palii, Brian McNeill, Morten Ritso, William C. Shelley, Nutan Prasain, Alphonse Chu, Elodie Vion, Kristy Rieck, Sharmin Nilufar, Theodore J. Perkins, Michael A. Rudnicki, David S. Allan, Mervin C. Yoder, Erik J. Suuronen, Marjorie Brand
Format: Article
Language:English
Published: Elsevier 2017-11-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671117304162

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http://www.sciencedirect.com/science/article/pii/S2213671117304162

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