Epigenetic Activation of Pro-angiogenic Signaling Pathways in Human Endothelial Progenitors Increases Vasculogenesis
Summary: Human endothelial colony-forming cells (ECFCs) represent a promising source of adult stem cells for vascular repair, yet their regenerative capacity is limited. Here, we set out to understand the molecular mechanism restricting the repair function of ECFCs. We found that key pro-angiogenic...
Main Authors: | Sylvain Fraineau, Carmen G. Palii, Brian McNeill, Morten Ritso, William C. Shelley, Nutan Prasain, Alphonse Chu, Elodie Vion, Kristy Rieck, Sharmin Nilufar, Theodore J. Perkins, Michael A. Rudnicki, David S. Allan, Mervin C. Yoder, Erik J. Suuronen, Marjorie Brand |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-11-01
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Series: | Stem Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213671117304162 |
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