The FKBP5 Gene Affects Alcohol Drinking in Knockout Mice and Is Implicated in Alcohol Drinking in Humans

The FKBP5 Gene Affects Alcohol Drinking in Knockout Mice and Is Implicated in Alcohol Drinking in Humans

FKBP5 encodes FK506-binding protein 5, a glucocorticoid receptor (GR)-binding protein implicated in various psychiatric disorders and alcohol withdrawal severity. The purpose of this study is to characterize alcohol preference and related phenotypes in Fkbp5 knockout (KO) mice and to examine the rol...

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Bibliographic Details
Main Authors: Bin Qiu, Susan E. Luczak, Tamara L. Wall, Aaron M. Kirchhoff, Yuxue Xu, Mimy Y. Eng, Robert B. Stewart, Weinian Shou, Stephen L. Boehm, Julia A. Chester, Weidong Yong, Tiebing Liang
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:International Journal of Molecular Sciences
Subjects:
Fkbp5 knockout
alcohol drinking behavior
human alcohol use disorder
Online Access:http://www.mdpi.com/1422-0067/17/8/1271

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http://www.mdpi.com/1422-0067/17/8/1271

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