The FKBP5 Gene Affects Alcohol Drinking in Knockout Mice and Is Implicated in Alcohol Drinking in Humans
FKBP5 encodes FK506-binding protein 5, a glucocorticoid receptor (GR)-binding protein implicated in various psychiatric disorders and alcohol withdrawal severity. The purpose of this study is to characterize alcohol preference and related phenotypes in Fkbp5 knockout (KO) mice and to examine the rol...
Main Authors: | Bin Qiu, Susan E. Luczak, Tamara L. Wall, Aaron M. Kirchhoff, Yuxue Xu, Mimy Y. Eng, Robert B. Stewart, Weinian Shou, Stephen L. Boehm, Julia A. Chester, Weidong Yong, Tiebing Liang |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2016-08-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | http://www.mdpi.com/1422-0067/17/8/1271 |
Similar Items
-
Positive metacognitions about alcohol mediate the relationship between FKBP5 variability and problematic drinking in a sample of young women
by: Dragan WŁ, et al.
Published: (2018-10-01) -
Relation between age at first alcohol drink & adult life drinking patterns in alcohol-dependent patients
by: Soundarya Soundararajan, et al.
Published: (2017-01-01) -
Alcohol and Energy Drinks: Motivations, Drinking Behaviours and Associated Risks
by: Brache, Kristina
Published: (2014) -
Consumption Patterns of Alcohol and Alcohol mixed with Energy Drinks in Australian Students and Non-Students
by: Sarah Benson, et al.
Published: (2020-01-01) -
Analysis of the cerebellar molecular stress response led to first evidence of a role for FKBP51 in brain FKBP52 expression in mice and humans
by: Leonie Herrmann, et al.
Published: (2021-11-01)