Ovulatory signals alter granulosa cell behavior through YAP1 signaling

Abstract Background The Hippo pathway plays critical roles in regulating cell proliferation, differentiation and survival among species. Hippo pathway proteins are expressed in the ovary and are involved in ovarian function. Deletion of Lats1 causes germ cell loss, ovarian stromal tumors and reduced...

Full description

Bibliographic Details
Main Authors: Tianyanxin Sun, Francisco J. Diaz
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Reproductive Biology and Endocrinology
Subjects:
Online Access:https://doi.org/10.1186/s12958-019-0552-1