Orally administered endoxifen inhibits tumor growth in melanoma-bearing mice

Orally administered endoxifen inhibits tumor growth in melanoma-bearing mice

Abstract Endoxifen, an active metabolite of tamoxifen, has been shown to be an effective anti-estrogenic agent in estrogen receptor-positive breast cancer patients. In melanoma, estrogen receptor expression is shown to be associated with disease progression. However, the therapeutic benefit of endox...

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Bibliographic Details
Main Authors: Paul Chen, Saifuddin Sheikh, Ateeq Ahmad, Shoukath M. Ali, Moghis U. Ahmad, Imran Ahmad
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Cellular & Molecular Biology Letters
Subjects:
Endoxifen
Melanoma tumor model
Tamoxifen
Safety
Efficacy
Online Access:http://link.springer.com/article/10.1186/s11658-017-0068-7

Internet

http://link.springer.com/article/10.1186/s11658-017-0068-7

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