<i>PFN2a</i> Suppresses C2C12 Myogenic Development by Inhibiting Proliferation and Promoting Apoptosis via the p53 Pathway

<i>PFN2a</i> Suppresses C2C12 Myogenic Development by Inhibiting Proliferation and Promoting Apoptosis via the p53 Pathway

Skeletal muscle plays a crucial role in physical activity and in regulating body energy and protein balance. Myoblast proliferation, differentiation, and apoptosis are indispensable processes for myoblast myogenesis. Profilin 2a (PFN2a) is a ubiquitous actin monomer-binding protein and promotes lung...

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Bibliographic Details
Main Authors: Huaqin Li, Lianjie Hou, Yu Zhang, Fangyi Jiang, Yifan Zhu, Qing X. Li, Ching Yuan Hu, Chong Wang
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cells
Subjects:
proliferation
myogenic development
skeletal muscle
apoptosis
HDAC1
Online Access:https://www.mdpi.com/2073-4409/8/9/959

Internet

https://www.mdpi.com/2073-4409/8/9/959

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