Iodine-124 PET quantification of organ-specific delivery and expression of NIS-encoding RNA

Abstract Background RNA-based vaccination strategies tailoring immune response to specific reactions have become an important pillar for a broad range of applications. Recently, the use of lipid-based nanoparticles opened the possibility to deliver RNA to specific sites within the body, overcoming t...

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Bibliographic Details
Main Authors: Matthias Miederer, Stefanie Pektor, Isabelle Miederer, Nicole Bausbacher, Isabell Sofia Keil, Hossam Hefesha, Heinrich Haas, Ugur Sahin, Mustafa Diken
Format: Article
Language:English
Published: SpringerOpen 2021-02-01
Series:EJNMMI Research
Subjects:
NIS
Online Access:https://doi.org/10.1186/s13550-021-00753-2