CpG-methylation regulates a class of Epstein-Barr virus promoters.

CpG-methylation regulates a class of Epstein-Barr virus promoters.

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian gene regulation. In general, cytosine-phosphatidyl-guanosine (CpG)-methylated promoters are transcriptionally repressed and nuclear proteins such as MECP2, MBD1, MBD2, and MBD4 bind CpG-methylate...

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Bibliographic Details
Main Authors: Martin Bergbauer, Markus Kalla, Anne Schmeinck, Christine Göbel, Ulrich Rothbauer, Sebastian Eck, Anna Benet-Pagès, Tim M Strom, Wolfgang Hammerschmidt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2944802?pdf=render

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http://europepmc.org/articles/PMC2944802?pdf=render

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