Proton-transfer pathways in the mitochondrial S. cerevisiae cytochrome c oxidase
Abstract In cytochrome c oxidase (CytcO) reduction of O2 to water is linked to uptake of eight protons from the negative side of the membrane: four are substrate protons used to form water and four are pumped across the membrane. In bacterial oxidases, the substrate protons are taken up through the...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-12-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-019-56648-9 |