Proton-transfer pathways in the mitochondrial S. cerevisiae cytochrome c oxidase

Abstract In cytochrome c oxidase (CytcO) reduction of O2 to water is linked to uptake of eight protons from the negative side of the membrane: four are substrate protons used to form water and four are pumped across the membrane. In bacterial oxidases, the substrate protons are taken up through the...

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Bibliographic Details
Main Authors: Markus L. Björck, Jóhanna Vilhjálmsdóttir, Andrew M. Hartley, Brigitte Meunier, Linda Näsvik Öjemyr, Amandine Maréchal, Peter Brzezinski
Format: Article
Language:English
Published: Nature Publishing Group 2019-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-56648-9