Dietary carbohydrate, particularly glucose, drives B cell lymphopoiesis and function

Summary: While diet modulates immunity, its impact on B cell ontogeny remains unclear. Using mixture modeling, a large-scale isocaloric dietary cohort mouse study identified carbohydrate as a major driver of B cell development and function. Increasing dietary carbohydrate increased B cell proportion...

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Bibliographic Details
Main Authors: Jian Tan, Duan Ni, Jibran Abdul Wali, Darren Anthony Cox, Gabriela Veronica Pinget, Jemma Taitz, Claire Immediato Daïen, Alistair Senior, Mark Norman Read, Stephen James Simpson, Nicholas Jonathan Cole King, Laurence Macia
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221008038