Statin action enriches HDL3 in polyunsaturated phospholipids and plasmalogens and reduces LDL-derived phospholipid hydroperoxides in atherogenic mixed dyslipidemia

Statin action enriches HDL3 in polyunsaturated phospholipids and plasmalogens and reduces LDL-derived phospholipid hydroperoxides in atherogenic mixed dyslipidemia

Atherogenic mixed dyslipidemia associates with oxidative stress and defective HDL antioxidative function in metabolic syndrome (MetS). The impact of statin treatment on the capacity of HDL to inactivate LDL-derived, redox-active phospholipid hydroperoxides (PCOOHs) in MetS is indeterminate. Insulin-...

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Bibliographic Details
Main Authors: Alexina Orsoni, Patrice Thérond, Ricardo Tan, Philippe Giral, Paul Robillard, Anatol Kontush, Peter J. Meikle, M. John Chapman
Format: Article
Language:English
Published: Elsevier 2016-11-01
Series:Journal of Lipid Research
Subjects:
antioxidative activity
low density lipoprotein
high density lipoprotein 3
lipidomics
metabolic syndrome disease
pitavastatin
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520345788

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http://www.sciencedirect.com/science/article/pii/S0022227520345788

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