Nrf2, a PPARγ alternative pathway to promote CD36 expression on inflammatory macrophages: implication for malaria.

Nrf2, a PPARγ alternative pathway to promote CD36 expression on inflammatory macrophages: implication for malaria.

CD36 is the major receptor mediating nonopsonic phagocytosis of Plasmodium falciparum-parasitized erythrocytes by macrophages. Its expression on macrophages is mainly controlled by the nuclear receptor PPARγ. Here, we demonstrate that inflammatory processes negatively regulate CD36 expression on hum...

Full description

Bibliographic Details
Main Authors: David Olagnier, Rose-Anne Lavergne, Etienne Meunier, Lise Lefèvre, Christophe Dardenne, Agnès Aubouy, Françoise Benoit-Vical, Bernhard Ryffel, Agnès Coste, Antoine Berry, Bernard Pipy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3174257?pdf=render

Internet

http://europepmc.org/articles/PMC3174257?pdf=render

Similar Items