Heat shock protein 70 is associated with replicase complex of Japanese encephalitis virus and positively regulates viral genome replication.

Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus that causes the most prevalent viral encephalitis in Asia. The NS5 protein of JEV is a key component of the viral replicase complex, which plays a crucial role in viral pathogenesis. In this study, tandem affinity purification (TAP) fo...

Full description

Bibliographic Details
Main Authors: Jing Ye, Zheng Chen, Bo Zhang, Huan Miao, Ali Zohaib, Qiuping Xu, Huanchun Chen, Shengbo Cao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3781048?pdf=render