BIRC3 and BIRC5: multi‐faceted inhibitors in cancer

Abstract Background The evasion from apoptosis is a common strategy adopted by most tumors, and inhibitors of apoptosis proteins (IAPs) are among the most studied molecular and therapeutic targets. BIRC3 (cellular IAP2) and BIRC5 (survivin) are two of the eight members of the human IAPs family. This...

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Bibliographic Details
Main Author: Raffaele Frazzi
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Cell & Bioscience
Subjects:
Online Access:https://doi.org/10.1186/s13578-020-00521-0