An in vitro Study on the Role of Hepatitis B Virus X Protein C-Terminal Truncation in Liver Disease Development

An in vitro Study on the Role of Hepatitis B Virus X Protein C-Terminal Truncation in Liver Disease Development

Hepatitis B virus X protein C-terminal 127 amino acid truncation is often found expressed in hepatocellular carcinoma (HCC) tissue samples. The present in vitro study tried to determine the role of this truncation mutant in the hepatitis B–related liver diseases such as fibrosis, cirrhosis, HCC, and...

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Bibliographic Details
Main Authors: Zaheenul Islam Siddiqui, Syed Ali Azam, Wajihul Hasan Khan, Masarrat Afroz, Sabihur Rahman Farooqui, Fatima Amir, Md Iqbal Azmi, Ayesha Anwer, Saniya Khan, Mahboubeh Mehmankhah, Shama Parveen, Syed Naqui Kazim
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Genetics
Subjects:
hepatitis B virus X protein mutation
HBx C-terminal truncation
HBx C-terminal deletion
liver disease development
hepatocellular carcinoma
cirrhosis
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.633341/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.633341/full

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