Phorbol Ester Enhances KAI1 Transcription by Recruiting Tip60/Pontin Complexes

Down-regulation of the KAI1 (CD82) metastasis suppressor is common in advanced human cancer, but underlying mechanism(s) regulating KAI1 expression are only now being elucidated. Recent data provide evidence that low levels of KAI1 mRNA in LNCaP cells are caused by binding of β-catenin/Reptin compl...

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Bibliographic Details
Main Authors: Alexandra Rowe, Jörg Weiske, Tobias S. Kramer, Otmar Huber, Paul Jackson
Format: Article
Language:English
Published: Elsevier 2008-12-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558608800875