Rapid and Accurate Approach for Screening of Microsatellite Unstable Tumours Using Quasimonomorphic Mononucleotide Repeats and Denaturating High Performance Liquid Chromatography (DHPLC)

MSI analysis is becoming increasingly important for the detection of both hereditary non-polyposis colorectal cancer and sporadic primary colorectal tumours with MSI high phenotype. The Bethesda panel of five microsatellite markers has been proposed to provide uniform criteria for MSI analysis. Here...

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Bibliographic Details
Main Authors: Gašper Berginc, Damjan Glavač
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.3233/DMA-2009-0600