An integrative framework for Bayesian variable selection with informative priors for identifying genes and pathways.

The discovery of genetic or genomic markers plays a central role in the development of personalized medicine. A notable challenge exists when dealing with the high dimensionality of the data sets, as thousands of genes or millions of genetic variants are collected on a relatively small number of sub...

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Bibliographic Details
Main Authors: Bin Peng, Dianwen Zhu, Bradley P Ander, Xiaoshuai Zhang, Fuzhong Xue, Frank R Sharp, Xiaowei Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23844055/?tool=EBI