An integrative framework for Bayesian variable selection with informative priors for identifying genes and pathways.
The discovery of genetic or genomic markers plays a central role in the development of personalized medicine. A notable challenge exists when dealing with the high dimensionality of the data sets, as thousands of genes or millions of genetic variants are collected on a relatively small number of sub...
Main Authors: | Bin Peng, Dianwen Zhu, Bradley P Ander, Xiaoshuai Zhang, Fuzhong Xue, Frank R Sharp, Xiaowei Yang |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23844055/?tool=EBI |
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