Heme Oxygenase-1 Restores Impaired GARP+CD4+CD25+ Regulatory T Cells from Patients with Acute Coronary Syndrome by Upregulating LAP and GARP Expression on Activated T Lymphocytes

Heme Oxygenase-1 Restores Impaired GARP+CD4+CD25+ Regulatory T Cells from Patients with Acute Coronary Syndrome by Upregulating LAP and GARP Expression on Activated T Lymphocytes

Background: Accumulating evidence shows that the pathological autoreactive immune response is responsible for plaque rupture and the subsequent onset of acute coronary syndrome (ACS). Naturally occurring CD4+CD25+regulatory T cells (nTregs) are indispensable in suppressing the pathological autoreact...

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Bibliographic Details
Main Authors: Yuzhou Liu, Xiaoqi Zhao, Yucheng Zhong, Kai Meng, Kunwu Yu, Huairui Shi, Bangwei Wu, Hasahya Tony, Jianghao Zhu, Ruirui Zhu, Yudong Peng, Yi Mao, Peng Cheng, Xiaobo Mao, Qiutang Zeng
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-01-01
Series:Cellular Physiology and Biochemistry
Subjects:
Heme oxygenase-1
GARP+ CD4+ CD25+Tregs
LAP
Foxp3
Acute coronary syndrome
Online Access:http://www.karger.com/Article/FullText/369719

Internet

http://www.karger.com/Article/FullText/369719

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