Myasthenia Gravis: From the Viewpoint of Pathogenicity Focusing on Acetylcholine Receptor Clustering, Trans-Synaptic Homeostasis and Synaptic Stability
Myasthenia gravis (MG) is a disease of the postsynaptic neuromuscular junction (NMJ) where nicotinic acetylcholine (ACh) receptors (AChRs) are targeted by autoantibodies. Search for other pathogenic antigens has detected the antibodies against muscle-specific tyrosine kinase (MuSK) and low-density l...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2020-05-01
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Series: | Frontiers in Molecular Neuroscience |
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Online Access: | https://www.frontiersin.org/article/10.3389/fnmol.2020.00086/full |