Modeling Cardiac Disease Mechanisms Using Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Progress, Promises and Challenges

Modeling Cardiac Disease Mechanisms Using Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Progress, Promises and Challenges

Cardiovascular diseases (CVDs) are a class of disorders affecting the heart or blood vessels. Despite progress in clinical research and therapy, CVDs still represent the leading cause of mortality and morbidity worldwide. The hallmarks of cardiac diseases include heart dysfunction and cardiomyocyte...

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Bibliographic Details
Main Authors: Elvira Immacolata Parrotta, Valeria Lucchino, Luana Scaramuzzino, Stefania Scalise, Giovanni Cuda
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
cardiovascular diseases
human induced pluripotent stem cells
cardiac differentiation
iPSC-derived cardiomyocytes
cardiac disease modeling
Online Access:https://www.mdpi.com/1422-0067/21/12/4354

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https://www.mdpi.com/1422-0067/21/12/4354

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