Synthesis and tumour cell uptake studies of gadolinium(III)–phosphonium complexes

Abstract The synthesis of a new series of Gd(III)-arylphosphonium complexes is described and the solution stability of selected compounds is reported. Their lipophilicity and uptake in human glial (SVG p12) and human glioblastoma multiforme (T98G) cell lines are presented. The in vitro cytotoxicity...

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Bibliographic Details
Main Authors: Andrew J. Hall, Amy G. Robertson, Leila R. Hill, Louis M. Rendina
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79893-9