Expression of an IRF-3 fusion protein and mouse estrogen receptor, inhibits hepatitis C viral replication in RIG-I-deficient Huh 7.5 cells

<p>Abstract</p> <p>Interferon Regulatory Factor-3 (IRF-3) plays a central role in the induction of interferon (IFN) production and succeeding interferon-stimulated genes (ISG) expression en route for restraining hepatitis C virus (HCV) infection. Here, we established a stable Huh7....

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Bibliographic Details
Main Authors: Liu Chen, Nelson David R, Dong Huijia, Yan Xiaobo, Yao Luyu, Li Xiaoyu
Format: Article
Language:English
Published: BMC 2011-09-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/8/1/445