Common Polymorphism’s Analysis of Thiopurine S-Methyltransferase (TPMT) in Iranian Population
Objective: Thiopurine S-methyltransferase (TPMT) catalyses the S-methylation of thiopurinedrugs. Low activity phenotypes are correlated with several mutations in the TPMTgene and adverse drug reactions. The molecular basis for dissimilar enzymatic activityof TPMT has been established in Caucasians,...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Royan Institute (ACECR), Tehran
2009-01-01
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| Series: | Cell Journal |
| Subjects: | |
| Online Access: | http://celljournal.org/library/upload/article/Azad.pdf |