Data-Independent Acquisition for the Quantification and Identification of Metabolites in Plasma

A popular fragmentation technique for non-targeted analysis is called data-independent acquisition (DIA), because it provides fragmentation data for all analytes in a specific mass range. In this work, we demonstrated the strengths and weaknesses of DIA. Two types of chromatography (fractionation/3...

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Bibliographic Details
Main Authors: Tom van der Laan, Isabelle Boom, Joshua Maliepaard, Anne-Charlotte Dubbelman, Amy C. Harms, Thomas Hankemeier
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/10/12/514