Microglia reprogram metabolic profiles for phenotype and function changes in central nervous system

Microglia reprogram metabolic profiles for phenotype and function changes in central nervous system

In response to various types of environmental and cellular stress, microglia rapidly activate and exhibit either pro- or anti-inflammatory phenotypes to maintain tissue homeostasis. Activation of microglia can result in changes in morphology, phagocytosis capacity, and secretion of cytokines. Furthe...

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Bibliographic Details
Main Authors: Sheng Yang, Chuan Qin, Zi-Wei Hu, Luo-Qi Zhou, Hai-Han Yu, Man Chen, Dale B. Bosco, Wei Wang, Long-Jun Wu, Dai-Shi Tian
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Neurobiology of Disease
Subjects:
Microglia
Inflammation
Metabolism
Reprogramming
Glycolysis
Oxidative phosphorylation
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996121000395

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http://www.sciencedirect.com/science/article/pii/S0969996121000395

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