Gender effect on the pharmacokinetics of thymoquinone: Preclinical investigation and in silico modeling in male and female rats

Thymoquinone is the most biologically active constituent of Nigella sativa (black seed). A monoterpene compound chemically known as 2-methyl-5-isopropyl-1, 4-quinone. In this study, the gender-dependent pharmacokinetic behavior of thymoquinone in rats was investigated. Thymoquinone was administered...

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Bibliographic Details
Main Authors: Ajaz Ahmad, Saeed Alqahtani, Basit Latief Jan, Mohammad Raish, Abdullah K. Rabba, Khalid M. Alkharfy
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Saudi Pharmaceutical Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016420300268