lncRNA-Xist/miR-101-3p/KLF6/C/EBPα axis promotes TAM polarization to regulate cancer cell proliferation and migration

lncRNA-Xist/miR-101-3p/KLF6/C/EBPα axis promotes TAM polarization to regulate cancer cell proliferation and migration

The phenotypic switch in tumor-associated macrophages (TAMs) mediates immunity escape of cancer. However, the underlying mechanisms in the TAM phenotypic switch have not been systematically elucidated. In this study, long noncoding RNA (lncRNA)-Xist, CCAAT/enhancer-binding protein (C/EBP)α, and Krup...

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Bibliographic Details
Main Authors: Yanyun Zhao, Zhaojin Yu, Rong Ma, Yifan Zhang, Lin Zhao, Yuanyuan Yan, Xuemei Lv, Liwen Zhang, Panpan Su, Jia Bi, Hong Xu, Miao He, Minjie Wei
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
tumor-associated macrophages
polarization
lncRNA Xist
ceRNA
miR-101
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120303863

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http://www.sciencedirect.com/science/article/pii/S2162253120303863

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