Inferring noncoding RNA families and classes by means of genome-scale structure-based clustering.

The RFAM database defines families of ncRNAs by means of sequence similarities that are sufficient to establish homology. In some cases, such as microRNAs and box H/ACA snoRNAs, functional commonalities define classes of RNAs that are characterized by structural similarities, and typically consist o...

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Bibliographic Details
Main Authors: Sebastian Will, Kristin Reiche, Ivo L Hofacker, Peter F Stadler, Rolf Backofen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-04-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.0030065