Profiling of circulating tumor DNA in plasma of non‐small cell lung cancer patients, monitoring of epidermal growth factor receptor p.T790M mutated allelic fraction using beads, emulsion, amplification, and magnetics companion assay and evaluation in future application in mimicking circulating tumor cells

Profiling of circulating tumor DNA in plasma of non‐small cell lung cancer patients, monitoring of epidermal growth factor receptor p.T790M mutated allelic fraction using beads, emulsion, amplification, and magnetics companion assay and evaluation in future application in mimicking circulating tumor cells

Abstract Cell‐free plasma DNA (cfDNA) and mimicking circulating tumor cells (mCTCs) have demonstrated tremendous potential for molecular diagnosis of cancer and have been rapidly implemented in specific settings. However, widespread clinical adoption still faces some obstacles. The purpose was to co...

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Bibliographic Details
Main Authors: Jessica Garcia, Anne‐Sophie Wozny, Florence Geiguer, Aurélia Delherme, David Barthelemy, Patrick Merle, Claire Tissot, Frederick S. Jones, Chassidy Johnson, Xiaobin Xing, Zhenyu Xu, Daniel L. Edelstein, Marie Brevet, Pierre‐Jean Souquet, Claire Rodriguez‐Lafrasse, Léa Payen, Sébastien Couraud
Format: Article
Language:English
Published: Wiley 2019-07-01
Series:Cancer Medicine
Subjects:
circulating‐free DNA
digital PCR
liquid biopsy
lung cancer
NGS
Online Access:https://doi.org/10.1002/cam4.2244

Internet

https://doi.org/10.1002/cam4.2244

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